RNF207

RNF207 (Ring Finger Protein 207) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ion channel binding and Hsp70 protein binding.

Full Name

Ring Finger Protein 207

Function

Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.

Biological Process

Biological Process cell-cell signaling involved in cardiac conductionISS:BHF-UCL
Biological Process positive regulation of delayed rectifier potassium channel activityManual Assertion Based On ExperimentIGI:BHF-UCL
Biological Process positive regulation of gene expressionManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process positive regulation of potassium ion transmembrane transporter activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarizationISS:BHF-UCL
Biological Process positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarizationManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process regulation of cardiac muscle contractionISS:BHF-UCL
Biological Process regulation of heart loopingISS:BHF-UCL

Cellular Location

Cytoplasm
Probably located in the endoplasmic reticulum and/or possibly the cis-Golgi apparatus.