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RuV E2

Rubella virus is the only member of the Rubrivirus genus of the Togavirus family. Unlike most Togaviruses it is NOT arthropod borne, but is acquired via the respiratory route. It is an enveloped (toga=cloak), non-segmented, positive sense, RNA virus and replicates in the cytoplasm. It consists of 3 structural proteins; E1,E2 membrane bound glycoproteins, and C capsid protein. E1 envelope glycoprotein is a class II viral fusion protein. Fusion activity is inactive as long as E1 is bound to E2 in mature virion. After virus attachment to target cell and endocytosis, acidification of the endosome induces dissociation of E1/E2 heterodimer and trimerization of the E1 subunits. This E1 homotrimer is fusion active, and promotes release of viral nucleocapsid in the cytoplasm after cell and viral membrane fusion. The E1 cytoplasmic tail modulates virus release, and the tyrosines residues are critical for this function.
Full Name
RuV Active E2 protein

Anti-RuV E2 antibodies

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Mouse Anti-RuVE2 Recombinant Antibody (CBMY-C0230) (CBMAB-V208-C0233-YY)

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Target: RuV E2
Host: Mouse
Antibody Isotype: IgG1
Specificity: RuV
Clone: CBMY-C0230
Application*: E, WB
Datasheet SDS

Mouse Anti-RuV E2 Recombinant Antibody (CBMC-C0374) (CBMAB-V208-1349-CQ)

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Target: RuV E2
Host: Mouse
Antibody Isotype: IgG1
Specificity: RuV
Clone: CBMC-C0374
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-RuV E2 Recombinant Antibody (CBMC-C0274) (CBMAB-V208-1086-CQ)

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Target: RuV E2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: RuV
Clone: CBMC-C0274
Application*: WB
Datasheet SDS

Mouse Anti-RuV E2 Recombinant Antibody (CBMC-C0462) (CBMAB-V208-0593-CQ)

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Target: RuV E2
Host: Mouse
Specificity: RuV
Clone: CBMC-C0462
Application*: E
Datasheet SDS

Mouse Anti-RuV E2 Recombinant Antibody (CBMC-C0267) (CBMAB-V208-0500-CQ)

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Target: RuV E2
Host: Mouse
Antibody Isotype: IgG1
Specificity: RuV
Clone: CBMC-C0267
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-RuV E2 Recombinant Antibody (CBMC-C0331) (CBMAB-V208-0348-CQ)

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Target: RuV E2
Host: Mouse
Antibody Isotype: IgG1
Specificity: RuV
Clone: CBMC-C0331
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-RuV E2 Recombinant Antibody (CBMC-C0399) (CBMAB-V208-0294-CQ)

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Target: RuV E2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: RuV
Clone: CBMC-C0399
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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