SEMA3B

The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Full Name
Semaphorin 3B
Function
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Biological Process
Biological Process axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process chemorepulsion of axonManual Assertion Based On ExperimentTAS:ARUK-UCL
Biological Process negative chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of axon extension involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neural crest cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process semaphorin-plexin signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
Endoplasmic reticulum
Accumulates in the endoplasmic reticulum.
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Anti-SEMA3B antibodies

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Rabbit Anti-SEMA3B Recombinant Antibody (D5A2P) (CBMAB-CP2390-LY)

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Target: SEMA3B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D5A2P
Application*: WB, IP
Datasheet SDS

Rat Anti-SEMA3B Recombinant Antibody (CBXS-1973) (CBMAB-S4745-CQ)

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Target: SEMA3B
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-1973
Application*: WB, IC
Datasheet SDS

Rabbit Anti-SEMA3B Recombinant Antibody (CBXS-5407) (CBMAB-S2619-CQ)

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Target: SEMA3B
Host: Rabbit
Specificity: Human
Clone: CBXS-5407
Application*: WB, IP
Datasheet SDS

Mouse Sema3b ELISA Kit (V2LY-0626-LY3030)

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Target: Sema3b
Sensitivity: 0.058 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

Human SEMA3B ELISA Kit (V2LY-0626-LY2293)

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Target: SEMA3B
Sensitivity: 0.046 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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