SERBP1
SERBP1 (SERPINE1 MRNA Binding Protein 1) is a Protein Coding gene. Among its related pathways are Apoptosis-related network due to altered Notch3 in ovarian cancer. Gene Ontology (GO) annotations related to this gene include mRNA 3-UTR binding. An important paralog of this gene is HABP4.
Full Name
SERPINE1 mRNA binding protein 1
Function
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation (PubMed:28695742).
Biological Process
Biological Process PML body organizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of mRNA stability1 PublicationNAS:HGNC-UCL
Biological Process regulation of mRNA stability1 PublicationNAS:HGNC-UCL
Cellular Location
Cytoplasm
Nucleus
Cytoplasm, perinuclear region
Nucleus
Cytoplasm, perinuclear region
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Anti-SERBP1 antibodies
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Target: SERBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1G5-2D7
Application*: WB, E
Target: SERBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D2-2E9
Application*: WB, E
Target: SERBP1
Host: Mouse
Specificity: Human
Clone: CBXS-2799
Application*: E, IH, WB
Target: SERBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse, Rat, Dog, Human, Monkey
Clone: CBXS-5081
Application*: WB, P
Target: SERBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Dog, Mouse
Clone: CBXS-4079
Application*: WB, IH
Target: SERBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5768
Application*: WB, IH
Target: SERBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-P828
Application*: E, IC, WB
Target: SERBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2E11
Application*: P, WB
Target: SERBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1E7
Application*: P, WB
Target: SERBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D2-2E9
Application*: E, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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