SFXN3

SFXN3 (Sideroflexin 3) is a Protein Coding gene. Among its related pathways are Validated targets of C-MYC transcriptional repression. Gene Ontology (GO) annotations related to this gene include cation transmembrane transporter activity and ion transmembrane transporter activity. An important paralog of this gene is SFXN1.
Full Name
sideroflexin 3
Function
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778).
Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778).
Biological Process
Biological Process mitochondrial transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process one-carbon metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process serine import into mitochondrionManual Assertion Based On ExperimentIDA:UniProtKB
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Anti-SFXN3 antibodies

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Mouse Anti-SFXN3 Recombinant Antibody (CBXS-3155) (CBMAB-S5897-CQ)

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Target: SFXN3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-3155
Application*: E, WB
Datasheet SDS

Rabbit Anti-SFXN3 Recombinant Antibody (CBXS-1370) (CBMAB-S4228-CQ)

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Target: SFXN3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1370
Application*: WB, P
Datasheet SDS

Mouse Anti-SFXN3 Recombinant Antibody (CBXS-0330) (CBMAB-S3301-CQ)

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Target: SFXN3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-0330
Application*: SE, WB, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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