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SLCO1A5

facilitates renal uptake and excretion of the uremic toxin indoxyl sulfate; may facilitate intestinal absorption of bile acids; transports thyroid hormones and taurocholate.
Full Name
solute carrier organic anion transporter family, member 1a5
Function
Na+-independent transporter that mediates the cellular uptake of a broad range of organic anions such as the endogenous bile salts cholate and deoxycholate, either in their unconjugated or conjugated forms (taurocholate and glycocholate), at the plasma membrane. Responsible for intestinal absorption of bile acids (By similarity).
Capable of thyroid hormone transport (both T3 or 3,3',5'-triiodo-L-thyronine, and T4 or L-tyroxine) (By similarity).
Plays roles in blood-brain and -cerebrospinal fluid barrier transport of organic anions and signal mediators, and in hormone uptake by neural cells (PubMed:15255953).
Biological Process
Biological Process bile acid and bile salt transportISO:MGI
Biological Process intestinal absorptionISO:MGI
Biological Process monocarboxylic acid transportISO:MGI
Biological Process organic anion transportISO:MGI
Biological Process sodium-independent organic anion transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane

Anti-SLCO1A5 antibodies

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Target: SLCO1A5
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBXO-0310
Application*: WB, IP, IF, E
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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