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Mouse Anti-SLCO1A5 Recombinant Antibody (CBXO-0310) (CBMAB-O0297-CQ)

This product is a mouse antibody that recognizes SLCO1A5. The antibody CBXO-0310 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all SLCO1A5 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBXO-0310
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier organic anion transporter family, member 1a5
Introduction
facilitates renal uptake and excretion of the uremic toxin indoxyl sulfate; may facilitate intestinal absorption of bile acids; transports thyroid hormones and taurocholate.
Entrez Gene ID
Mouse108096
Rat80900
UniProt ID
MouseQ91YY5
RatO88397
Alternative Names
Oatp3; OATP-3; Slc21a7; Slco1a2
Function
Na+-independent transporter that mediates the cellular uptake of a broad range of organic anions such as the endogenous bile salts cholate and deoxycholate, either in their unconjugated or conjugated forms (taurocholate and glycocholate), at the plasma membrane. Responsible for intestinal absorption of bile acids (By similarity).
Capable of thyroid hormone transport (both T3 or 3,3',5'-triiodo-L-thyronine, and T4 or L-tyroxine) (By similarity).
Plays roles in blood-brain and -cerebrospinal fluid barrier transport of organic anions and signal mediators, and in hormone uptake by neural cells (PubMed:15255953).
Biological Process
Biological Process bile acid and bile salt transportISO:MGI
Biological Process intestinal absorptionISO:MGI
Biological Process monocarboxylic acid transportISO:MGI
Biological Process organic anion transportISO:MGI
Biological Process sodium-independent organic anion transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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