Mouse Anti-SLCO1A5 Recombinant Antibody (CBXO-0310) (CBMAB-O0297-CQ)

Name: Mouse Anti-SLCO1A5 Recombinant Antibody (CBXO-0310)
SKU: CBMAB-O0297-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBXO-0310

Application

WB, IP, IF, ELISA

Specificity

Mouse, Rat, Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier organic anion transporter family, member 1a5

Introduction

facilitates renal uptake and excretion of the uremic toxin indoxyl sulfate; may facilitate intestinal absorption of bile acids; transports thyroid hormones and taurocholate.

Entrez Gene ID

Mouse	108096
Rat	80900

UniProt ID

Mouse	Q91YY5
Rat	O88397

Alternative Names

Oatp3; OATP-3; Slc21a7; Slco1a2

Function

Na+-independent transporter that mediates the cellular uptake of a broad range of organic anions such as the endogenous bile salts cholate and deoxycholate, either in their unconjugated or conjugated forms (taurocholate and glycocholate), at the plasma membrane. Responsible for intestinal absorption of bile acids (By similarity).
Capable of thyroid hormone transport (both T3 or 3,3',5'-triiodo-L-thyronine, and T4 or L-tyroxine) (By similarity).
Plays roles in blood-brain and -cerebrospinal fluid barrier transport of organic anions and signal mediators, and in hormone uptake by neural cells (PubMed:15255953).

Biological Process

Biological Process bile acid and bile salt transportISO:MGI
Biological Process intestinal absorptionISO:MGI
Biological Process monocarboxylic acid transportISO:MGI
Biological Process organic anion transportISO:MGI
Biological Process sodium-independent organic anion transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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