SPG3A

The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]
Full Name
atlastin GTPase 1
Cellular Location
Integral component of membrane

Anti-SPG3A antibodies

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Mouse Anti-SPG3A Recombinant Antibody (1B9) (CBMAB-A8533-LY)

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Target: ATL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: 1B9
Application*: WB, E
Datasheet SDS

Mouse Anti-SPG3A Recombinant Antibody (1B11) (CBMAB-A8532-LY)

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Target: ATL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: 1B11
Application*: WB, E
Datasheet SDS

Human Recombinant SPG3A protein, GST Tag (V2LY-0526-LY6926)

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Target: SPG3A
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-447
Tag: GST Tag
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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