SPINT1

The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
Full Name
Serine Peptidase Inhibitor, Kunitz Type 1
Function
Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).
Biological Process
Biological Process branching involved in labyrinthine layer morphogenesisIEA:Ensembl
Biological Process cellular response to BMP stimulusIEA:Ensembl
Biological Process epidermis developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process epithelium developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process extracellular matrix organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of neural precursor cell proliferationIEA:Ensembl
Biological Process neural tube closureIEA:Ensembl
Biological Process placenta blood vessel developmentIEA:Ensembl
Biological Process positive regulation of glial cell differentiationIEA:Ensembl
Cellular Location
Secreted
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Anti-SPINT1 antibodies

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Mouse Anti-SPINT1 Recombinant Antibody (CBXS-2592) (CBMAB-S5348-CQ)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-2592
Application*: WB
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-0688) (CBMAB-S3625-CQ)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0688
Application*: E
Datasheet SDS

Mouse Anti-SPINT1 (AA 37-449) Recombinant Antibody (CBXS-0687) (CBMAB-S3624-CQ)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0687
Application*: E
Datasheet SDS

Rat Anti-SPINT1 Recombinant Antibody (CBXS-5255) (CBMAB-S2470-CQ)

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Target: SPINT1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXS-5255
Application*: WB
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-5040) (CBMAB-S2261-CQ)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5040
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-5031) (CBMAB-S2253-CQ)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5031
Application*: IF, P, WB
Datasheet SDS

Human Anti-SPINT1 Recombinant Antibody (CBXS-4084) (CBMAB-S1341-CQ)

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Target: SPINT1
Host: Human
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4084
Application*: F
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-4045) (CBMAB-S1306-CQ)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4045
Application*: F, P, WB
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-3971) (CBMAB-S1234-CQ)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3971
Application*: F, WB
Datasheet SDS

Mouse Anti-SPINT1 (AA 37-449) Recombinant Antibody (CBXS-3752) (CBMAB-S1025-CQ)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3752
Application*: IP, WB
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-5834) (CBMAB-S0689-CQ)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-5834
Application*: E
Datasheet SDS

Rabbit Anti-SPINT1 Recombinant Antibody (CBFYH-2778) (CBMAB-H3844-FY)

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Target: SPINT1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-2778
Application*: E
Datasheet SDS

Rabbit Anti-SPINT1 Recombinant Antibody (CBFYH-2777) (CBMAB-H3843-FY)

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Target: SPINT1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-2777
Application*: E
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2776) (CBMAB-H3842-FY)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-2776
Application*: F, IP, WB
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2775) (CBMAB-H3841-FY)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2775
Application*: WB
Datasheet SDS

Rat Anti-SPINT1 Recombinant Antibody (CBFYH-2774) (CBMAB-H3840-FY)

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Target: SPINT1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYH-2774
Application*: WB
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2771) (CBMAB-H3837-FY)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2771
Application*: E
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2770) (CBMAB-H3836-FY)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Dog
Clone: CBFYH-2770
Application*: WB, F, IF
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2769) (CBMAB-H3835-FY)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2769
Application*: WB, P, IF
Datasheet SDS

Mouse Anti-SPINT1 Monoclonal Antibody (CBFYH-3306) (CBMAB-H3833-FY)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-3306
Application*: WB
Datasheet SDS

Mouse Anti-SPINT1 Recombinant Antibody (6G4E11) (CBMAB-H3832-FY)

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Target: SPINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6G4E11
Application*: E
Datasheet SDS

Rat Anti-SPINT1 Monoclonal Antibody (CBFYH-3307) (CBMAB-H3834-FY)

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Target: SPINT1
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYH-3307
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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