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SPINT1

The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.

Full Name

Serine Peptidase Inhibitor, Kunitz Type 1

Function

Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).

Biological Process

Biological Process branching involved in labyrinthine layer morphogenesisIEA:Ensembl
Biological Process cellular response to BMP stimulusIEA:Ensembl
Biological Process epidermis developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process epithelium developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process extracellular matrix organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of neural precursor cell proliferationIEA:Ensembl
Biological Process neural tube closureIEA:Ensembl
Biological Process placenta blood vessel developmentIEA:Ensembl
Biological Process positive regulation of glial cell differentiationIEA:Ensembl

Cellular Location

Secreted

Anti-SPINT1 antibodies

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-2592) (CBMAB-S5348-CQ)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-2592

Application*: WB

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-0688) (CBMAB-S3625-CQ)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-0688

Application*: E

Mouse Anti-SPINT1 (AA 37-449) Recombinant Antibody (CBXS-0687) (CBMAB-S3624-CQ)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-0687

Application*: E

Rat Anti-SPINT1 Recombinant Antibody (CBXS-5255) (CBMAB-S2470-CQ)

SDS

Target: SPINT1

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBXS-5255

Application*: WB

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-5040) (CBMAB-S2261-CQ)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-5040

Application*: F, IF, WB

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-5031) (CBMAB-S2253-CQ)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-5031

Application*: IF, P, WB

Human Anti-SPINT1 Recombinant Antibody (CBXS-4084) (CBMAB-S1341-CQ)

SDS

Target: SPINT1

Host: Human

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-4084

Application*: F

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-4045) (CBMAB-S1306-CQ)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4045

Application*: F, P, WB

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-3971) (CBMAB-S1234-CQ)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-3971

Application*: F, WB

Mouse Anti-SPINT1 (AA 37-449) Recombinant Antibody (CBXS-3752) (CBMAB-S1025-CQ)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-3752

Application*: IP, WB

Mouse Anti-SPINT1 Recombinant Antibody (CBXS-5834) (CBMAB-S0689-CQ)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXS-5834

Application*: E

Rabbit Anti-SPINT1 Recombinant Antibody (CBFYH-2778) (CBMAB-H3844-FY)

SDS

Target: SPINT1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2778

Application*: E

Rabbit Anti-SPINT1 Recombinant Antibody (CBFYH-2777) (CBMAB-H3843-FY)

SDS

Target: SPINT1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2777

Application*: E

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2776) (CBMAB-H3842-FY)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYH-2776

Application*: F, IP, WB

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2775) (CBMAB-H3841-FY)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2775

Application*: WB

Rat Anti-SPINT1 Recombinant Antibody (CBFYH-2774) (CBMAB-H3840-FY)

SDS

Target: SPINT1

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBFYH-2774

Application*: WB

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2771) (CBMAB-H3837-FY)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2771

Application*: E

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2770) (CBMAB-H3836-FY)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Dog

Clone: CBFYH-2770

Application*: WB, F, IF

Mouse Anti-SPINT1 Recombinant Antibody (CBFYH-2769) (CBMAB-H3835-FY)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2769

Application*: WB, P, IF

Rat Anti-SPINT1 Monoclonal Antibody (CBFYH-3307) (CBMAB-H3834-FY)

SDS

Target: SPINT1

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBFYH-3307

Application*: WB

Mouse Anti-SPINT1 Monoclonal Antibody (CBFYH-3306) (CBMAB-H3833-FY)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-3306

Application*: WB

Mouse Anti-SPINT1 Recombinant Antibody (6G4E11) (CBMAB-H3832-FY)

SDS

Target: SPINT1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 6G4E11

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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