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Human Anti-SPINT1 Recombinant Antibody (CBXS-4084) (CBMAB-S1341-CQ)

This product is a human antibody that recognizes SPINT1. The antibody CBXS-4084 can be used for immunoassay techniques such as: FC.
See all SPINT1 antibodies

Summary

Host Animal
Human
Specificity
Human
Clone
CBXS-4084
Antibody Isotype
IgG2b
Application
FC

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 50% glycerol, pH 7.2
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Serine Peptidase Inhibitor, Kunitz Type 1
Introduction
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
Entrez Gene ID
UniProt ID
Alternative Names
Serine Peptidase Inhibitor, Kunitz Type 1; Hepatocyte Growth Factor Activator Inhibitor Type 1; Serine Protease Inhibitor, Kunitz Type 1; HAI-1; HAI1; Kunitz-Type Protease Inhibitor 1; MANSC2; HAI;
Function
Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).
Biological Process
Biological Process branching involved in labyrinthine layer morphogenesisIEA:Ensembl
Biological Process cellular response to BMP stimulusIEA:Ensembl
Biological Process epidermis developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process epithelium developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process extracellular matrix organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of neural precursor cell proliferationIEA:Ensembl
Biological Process neural tube closureIEA:Ensembl
Biological Process placenta blood vessel developmentIEA:Ensembl
Biological Process positive regulation of glial cell differentiationIEA:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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