SRPRB

The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.

Full Name

SRP Receptor Beta Subunit

Function

Component of the signal recognition particle (SRP) complex receptor (SR) (By similarity).
Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity).
May mediate the membrane association of SR (By similarity).

Biological Process

Biological Process protein targeting to ERManual Assertion Based On ExperimentIBA:GO_Central
Biological Process SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition1 PublicationIC:ComplexPortal

Cellular Location

Endoplasmic reticulum membrane

Topology

Helical: 37-57

Anti-SRPRB antibodies

Mouse Anti-SRPRB Recombinant Antibody (CBXS-5181) (CBMAB-S2399-CQ)

Datasheet

SDS

Target: SRPRB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-5181

Application*: WB

Mouse Anti-SRPRB Recombinant Antibody (CBXS-4505) (CBMAB-S1746-CQ)

Datasheet

SDS

Target: SRPRB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4505

Application*: P, WB

Mouse Anti-SRPRB Recombinant Antibody (CBXS-4496) (CBMAB-S1738-CQ)

Datasheet

SDS

Target: SRPRB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4496

Application*: WB, IH

Mouse Anti-SRPRB Recombinant Antibody (CBXS-4419) (CBMAB-S1661-CQ)

Datasheet

SDS

Target: SRPRB

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-4419

Application*: P, WB

Mouse Anti-SRPRB Recombinant Antibody (CBXS-4023) (CBMAB-S1284-CQ)

Datasheet

SDS

Target: SRPRB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4023

Application*: WB, F, IH, P

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)