Mouse Anti-SRPRB Recombinant Antibody (CBXS-4496) (CBMAB-S1738-CQ)

Name: Mouse Anti-SRPRB Recombinant Antibody (CBXS-4496)
SKU: CBMAB-S1738-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-4496

Application

WB, IHC

Immunogen

Recombinant full length human SRPRB (NP_067026)

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SRP Receptor Beta Subunit

Introduction

The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.

Entrez Gene ID

58477

UniProt ID

Q9Y5M8

Alternative Names

SRP Receptor Beta Subunit; Signal Recognition Particle Receptor, B Subunit; SR-Beta; Signal Recognition Particle Receptor, Beta Subunit; Signal Recognition Particle Receptor Subunit Beta; Protein APMCF1; APMCF1;

Function

Component of the signal recognition particle (SRP) complex receptor (SR) (By similarity).
Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity).
May mediate the membrane association of SR (By similarity).

Biological Process

Biological Process protein targeting to ERManual Assertion Based On ExperimentIBA:GO_Central
Biological Process SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition1 PublicationIC:ComplexPortal

Cellular Location

Endoplasmic reticulum membrane

Topology

Helical: 37-57

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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