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Mouse Anti-SRPRB Recombinant Antibody (CBXS-4419) (CBMAB-S1661-CQ)

This product is a mouse antibody that recognizes SRPRB. The antibody CBXS-4419 can be used for immunoassay techniques such as: IHC-P, WB.
See all SRPRB antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4419
Antibody Isotype
IgG2b
Application
IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SRP Receptor Beta Subunit
Introduction
The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.
Entrez Gene ID
58477
UniProt ID
Q9Y5M8
Alternative Names
SRP Receptor Beta Subunit; Signal Recognition Particle Receptor, B Subunit; SR-Beta; Signal Recognition Particle Receptor, Beta Subunit; Signal Recognition Particle Receptor Subunit Beta; Protein APMCF1; APMCF1;
Function
Component of the signal recognition particle (SRP) complex receptor (SR) (By similarity).
Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity).
May mediate the membrane association of SR (By similarity).
Biological Process
Biological Process protein targeting to ERManual Assertion Based On ExperimentIBA:GO_Central
Biological Process SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition1 PublicationIC:ComplexPortal
Cellular Location
Endoplasmic reticulum membrane
Topology
Helical: 37-57
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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