SYNC

This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene.
Full Name
Syncoilin, Intermediate Filament Protein
Function
Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contraction. Does not form homofilaments nor heterofilaments with other IF proteins.
Biological Process
Intermediate filament-based process
Cellular Location
Cytoplasm, perinuclear region
In skeletal muscle, colocalizes with DES and DTNA, and is localized at the myotendinous and neuromuscular junctions, sarcolemma and Z-lines. In myotubes, detected in a punctate cytoplasmic pattern (By similarity).
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Anti-SYNC antibodies

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Mouse Anti-SYNC Recombinant Antibody (CBXS-2097) (CBMAB-S4862-CQ)

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Target: SYNC
Host: Mouse
Specificity: Human
Clone: CBXS-2097
Application*: WB, IP, IF, E
Mouse Anti-SYNC Recombinant Antibody (CBXS-2097)
Datasheet SDS

Mouse Anti-SYNC Recombinant Antibody (CBXS-5147) (CBMAB-S2365-CQ)

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Target: SYNC
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5147
Application*: WB, IH
Mouse Anti-SYNC Recombinant Antibody (CBXS-5147)
Datasheet SDS

Mouse Anti-SYNC Recombinant Antibody (CBXS-5038) (CBMAB-S2259-CQ)

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Target: SYNC
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5038
Application*: WB
Mouse Anti-SYNC Recombinant Antibody (CBXS-5038)
Datasheet SDS

Mouse Anti-SYNC Recombinant Antibody (CBXS-4076) (CBMAB-S1334-CQ)

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Target: SYNC
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4076
Application*: WB
Mouse Anti-SYNC Recombinant Antibody (CBXS-4076)
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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