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TAS1R3

TAS1R3 is a putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Full Name
Taste Receptor, Type 1, Member 3
Function
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity).
Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Biological Process
Biological Process detection of chemical stimulus involved in sensory perception of sweet tasteIDA:HGNC-UCL1 Publication
Biological Process G protein-coupled receptor signaling pathwayIC:HGNC-UCL1 Publication
Biological Process sensory perception of sweet tasteIDA:UniProtKB3 Publications
Biological Process sensory perception of umami tasteIDA:UniProtKB1 Publication
Cellular Location
Cell membrane
Topology
Extracellular: 21-570
Helical: 571-591
Cytoplasmic: 592-603
Helical: 604-624
Extracellular: 625-639
Helical: 640-660
Cytoplasmic: 661-682
Helical: 683-703
Extracellular: 704-729
Helical: 730-750
Cytoplasmic: 751-762
Helical: 763-783
Extracellular: 784-789
Helical: 790-810
Cytoplasmic: 811-852

Anti-TAS1R3 antibodies

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Target: Tas1r3
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBYJT-1735
Application*: WB, IP, IF, E
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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