TLR12

Tlr12 participates in the innate immune response to microbial agents. Tlr12 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It plays a role in preventing infection of internal organs of the urogenital system.

Full Name

Toll-Like Receptor 12

Function

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system.

Biological Process

Biological Process defense response to protozoanSource:MGI1 Publication
Biological Process inflammatory responseSource:GO_Central1 Publication
Biological Process innate immune responseSource:UniProtKB-KW
Biological Process toll-like receptor signaling pathwaySource:GO_Central1 Publication

Cellular Location

Membrane

Topology

Extracellular: 22-709
Helical: 710-730
Cytoplasmic: 731-906

Anti-TLR12 antibodies

Rabbit Anti-Tlr12 Recombinant Antibody (CBYJT-3354) (CBMAB-T2648-YJ)

Datasheet

SDS

Target: Tlr12

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBYJT-3354

Application*: WB, F

Mouse Anti-Tlr12 Recombinant Antibody (CBYJT-3355) (CBMAB-T2649-YJ)

Datasheet

SDS

Target: Tlr12

Host: Mouse

Antibody Isotype: IgM

Specificity: Mouse

Clone: CBYJT-3355

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)