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TLR12

Tlr12 participates in the innate immune response to microbial agents. Tlr12 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It plays a role in preventing infection of internal organs of the urogenital system.

Full Name

Toll-Like Receptor 12

Function

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system.

Biological Process

Biological Process defense response to protozoanSource:MGI1 Publication
Biological Process inflammatory responseSource:GO_Central1 Publication
Biological Process innate immune responseSource:UniProtKB-KW
Biological Process toll-like receptor signaling pathwaySource:GO_Central1 Publication

Cellular Location

Membrane

Topology

Extracellular: 22-709
Helical: 710-730
Cytoplasmic: 731-906

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Anti-TLR12 antibodies

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Mouse Anti-Tlr12 Recombinant Antibody (CBYJT-3355) (CBMAB-T2649-YJ)

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Target: Tlr12

Host: Mouse

Antibody Isotype: IgM

Specificity: Mouse

Clone: CBYJT-3355

Application*: WB

Rabbit Anti-Tlr12 Recombinant Antibody (CBYJT-3354) (CBMAB-T2648-YJ)

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Target: Tlr12

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBYJT-3354

Application*: WB, F

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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