TNFAIP8

TNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Among its related pathways are Metabolism and Glycerophospholipid biosynthesis. Gene Ontology (GO) annotations related to TNFAIP8 include cysteine-type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of TNFAIP8 is TNFAIP8L3.
Full Name
TNF Alpha Induced Protein 8
Function
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Biological Process
Biological Process negative regulation of apoptotic processSource:ProtInc1 Publication
Biological Process positive regulation of apoptotic processSource:UniProtKB1 Publication
Cellular Location
Cytoplasm
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Anti-TNFAIP8 antibodies

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Target: TNFAIP8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-3646
Application*: E
Target: TNFAIP8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-3645
Application*: P
Target: TNFAIP8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-3644
Application*: E
Target: TNFAIP8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-3643
Application*: P
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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