TNFAIP8

TNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Among its related pathways are Metabolism and Glycerophospholipid biosynthesis. Gene Ontology (GO) annotations related to TNFAIP8 include cysteine-type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of TNFAIP8 is TNFAIP8L3.

Full Name

TNF Alpha Induced Protein 8

Function

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Biological Process

Biological Process negative regulation of apoptotic processSource:ProtInc1 Publication
Biological Process positive regulation of apoptotic processSource:UniProtKB1 Publication

Cellular Location

Cytoplasm

Anti-TNFAIP8 antibodies

Mouse Anti-TNFAIP8 Recombinant Antibody (CBYJT-3643) (CBMAB-T3000-YJ)

Datasheet

SDS

Target: TNFAIP8

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJT-3643

Application*: P

Mouse Anti-TNFAIP8 Recombinant Antibody (CBYJT-3644) (CBMAB-T3001-YJ)

Datasheet

SDS

Target: TNFAIP8

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJT-3644

Application*: E

Mouse Anti-TNFAIP8 Recombinant Antibody (CBYJT-3645) (CBMAB-T3002-YJ)

Datasheet

SDS

Target: TNFAIP8

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJT-3645

Application*: P

Mouse Anti-TNFAIP8 Recombinant Antibody (CBYJT-3646) (CBMAB-T3003-YJ)

Datasheet

SDS

Target: TNFAIP8

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJT-3646

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)