TNFRSF6B
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]
Full Name
TNFRSF6B Gene(Protein Coding) TNF Receptor Superfamily Member 6b
Function
Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:ProtInc1 Publication
Biological Process negative regulation of apoptotic process Source:ProtInc1 Publication
Cellular Location
Secreted
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Anti-TNFRSF6B antibodies
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Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F1
Application*: WB, E
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-3860
Application*: E, P, WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYJT-3859
Application*: WB, N
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3858
Application*: WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3857
Application*: E, WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MD3F4
Application*: WB, E, IH, IP
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: B08-35
Application*: P
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 7G5
Application*: P
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4V24
Application*: N, WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 37A565
Application*: WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 14L351
Application*: N, WB
Target: TNFRSF6B
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-195
Tag: His Tag
Target: TNFRSF6B
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-195
Tag: His Tag
Target: TNFRSF6B
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-300
Tag: hFc Tag
Target: TNFRSF6B
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-300
Tag: hFc Tag
Compare
Target: TNFRSF6B
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-300
Tag: hFc & AVI Tag
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2636
Application*: F
Target: TNFRSF6B
Specificity: Human
Target: TNFRSF6B
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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