TNFRSF6B

This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]
Full Name
TNFRSF6B Gene(Protein Coding) TNF Receptor Superfamily Member 6b
Function
Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:ProtInc1 Publication
Cellular Location
Secreted
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Anti-TNFRSF6B antibodies

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Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F1
Application*: WB, E
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-3860
Application*: E, P, WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYJT-3859
Application*: WB, N
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3858
Application*: WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3857
Application*: E, WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MD3F4
Application*: WB, E, IH, IP
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: B08-35
Application*: P
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 7G5
Application*: P
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4V24
Application*: N, WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 37A565
Application*: WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 14L351
Application*: N, WB
Target: TNFRSF6B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2636
Application*: F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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