TRIM55

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

TRIM55 Gene(Protein Coding) Tripartite Motif Containing 55

May regulate gene expression and protein turnover in muscle cells.

Biological Process diapedesis Source:Ensembl
Biological Process leukocyte migration involved in inflammatory response Source:Ensembl
Biological Process macrophage migration Source:Ensembl
Biological Process protein ubiquitination Source:GO_Central1 Publication
Biological Process signal transduction Source:UniProtKB1 Publication

Cytoplasm
Nucleus
Nuclear under atrophic conditions and upon mechanical signals. Localizes to the sarcomeric M-band in cardiomyocytes. Colocalizes in part with microtubules (By similarity).