TSPAN7

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]
Full Name
TSPAN7 Gene(Protein Coding)


Tetraspanin 7
Function
May be involved in cell proliferation and cell motility.
Cellular Location
Membrane
Involvement in disease
Intellectual developmental disorder, X-linked 58 (XLID58):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked intellectual disability, while syndromic intellectual disability presents with associated physical, neurological and/or psychiatric manifestations.
Topology
Cytoplasmic: 1-16
Helical: 17-40
Extracellular: 41-56
Helical: 57-75
Cytoplasmic: 76-86
Helical: 87-112
Extracellular: 113-213
Helical: 214-234
Cytoplasmic: 235-249
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Anti-TSPAN7 antibodies

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Mouse Anti-TSPAN7 Recombinant Antibody (SN1a M3-3D9) (CBMAB-C12620-LY)

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Target: TSPAN7
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SN1a M3-3D9
Application*: F
Datasheet SDS

Mouse Anti-TSPAN7 Recombinant Antibody (SN1a) (CBMAB-C2067-CQ)

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Target: TSPAN7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: SN1a
Application*: F
Datasheet SDS

Mouse Anti-TSPAN7 Recombinant Antibody (CBYJT-5084) (CBMAB-T4662-YJ)

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Target: TSPAN7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-5084
Application*: IH, P
Datasheet SDS

Mouse Anti-TSPAN7 Recombinant Antibody (CBYJT-5083) (CBMAB-T4661-YJ)

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Target: TSPAN7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-5083
Application*: WB, IH, P
Datasheet SDS

Mouse Anti-TSPAN7 Recombinant Antibody (CBYJT-5082) (CBMAB-T4660-YJ)

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Target: TSPAN7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-5082
Application*: F, MC
Datasheet SDS

Mouse Anti-TSPAN7 Recombinant Antibody (CBYJT-5081) (CBMAB-T4659-YJ)

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Target: TSPAN7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-5081
Application*: E
Datasheet SDS

Mouse Anti-TSPAN7 Monoclonal Antibody (482618) (CBMAB-1668-YC)

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Target: TSPAN7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 482618
Application*: F
Datasheet SDS

Mouse Anti-TSPAN7 Monoclonal Antibody (CL0262) (CBMAB-1667-YC)

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Target: TSPAN7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CL0262
Application*: IH, P, WB
Datasheet SDS

Mouse Recombinant TSPAN7 protein, His Tag (V2LY-0526-LY8992)

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Target: TSPAN7
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 113-213
Tag: His Tag
Datasheet SDS

Human Recombinant TSPAN7 protein, His Tag (V2LY-0526-LY7277)

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Target: TSPAN7
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 113-213
Tag: His Tag
Datasheet SDS

Rat Recombinant TSPAN7 protein, ECD, His Tag (V2LY-0526-LY9614)

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Target: TSPAN7
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 113-213
Tag: His Tag
Datasheet SDS

Cynomolgus Recombinant TSPAN7 protein, Fc Tag (V2LY-0526-LY1659)

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Target: TSPAN7
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 113-213
Tag: Fc Tag
Datasheet SDS

Cynomolgus Recombinant TSPAN7 protein, His Tag (V2LY-0526-LY1658)

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Target: TSPAN7
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 113-213
Tag: His Tag
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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