Mouse Anti-TSPAN7 Recombinant Antibody (CBYJT-5084) (CBMAB-T4662-YJ)

Name: Mouse Anti-TSPAN7 Recombinant Antibody (CBYJT-5084)
SKU: CBMAB-T4662-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYJT-5084

Application

IHC, IHC-P

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: TFLRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDCNPQDLHNLTVAATKVNQKGCYDLVTSFMET

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TSPAN7 Gene(Protein Coding)

Tetraspanin 7

Introduction

TSPAN7 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It mediate signal transduction events that function in the regulation of cell development, activation, growth and motility. TSPAN7 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. TSPAN7 is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.

Entrez Gene ID

7102

UniProt ID

P41732

Alternative Names

Tetraspanin 7; Transmembrane 4 Superfamily Member 2; Membrane Component Chromosome X Surface Marker 1; Cell Surface Glycoprotein A15; CD231 Antigen; DXS1692E; Tspan-7; TALLA-1; TM4SF2; MXS1; A15; T-Cell Acute Lymphoblastic Leukemia Associated Antigen 1

Function

May be involved in cell proliferation and cell motility.

Cellular Location

Membrane

Involvement in disease

Intellectual developmental disorder, X-linked 58 (XLID58):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked intellectual disability, while syndromic intellectual disability presents with associated physical, neurological and/or psychiatric manifestations.

Topology

Cytoplasmic: 1-16
Helical: 17-40
Extracellular: 41-56
Helical: 57-75
Cytoplasmic: 76-86
Helical: 87-112
Extracellular: 113-213
Helical: 214-234
Cytoplasmic: 235-249

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-TSPAN7 Recombinant Antibody (CBYJT-5082) (CAT#: CBMAB-T4660-YJ)

Mouse Anti-TSPAN7 Recombinant Antibody (CBYJT-5083) (CAT#: CBMAB-T4661-YJ)

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Mouse Anti-TSPAN7 Recombinant Antibody (SN1a) (CAT#: CBMAB-C2067-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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