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WDHD1

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

Full Name

WDHD1

Function

Core replisome component that acts as a replication initiation factor. Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork.

Biological Process

Biological Process DNA repair Source:GO_Central1 Publication
Biological Process DNA-templated DNA replication Source:GO_Central1 Publication
Biological Process mitotic cell cycle Source:GO_Central1 Publication

Cellular Location

Nucleus, nucleoplasm

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Anti-WDHD1 antibodies

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Mouse Anti-WDHD1 Monoclonal Antibody (1B10) (CBMAB-0299-LY)

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Target: WDHD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1B10

Application*: IP, M, WB, CI

Mouse Anti-WDHD1 Monoclonal Antibody (1A5) (CBMAB-0298-LY)

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Target: WDHD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1A5

Application*: IP, M, CI

Mouse Anti-WDHD1 Recombinant Antibody (2F10) (CBMAB-A9913-LY)

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Target: WDHD1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2F10

Application*: WB, E

Mouse Anti-WDHD1 Recombinant Antibody (CBYY-1604) (CBMAB-1675-YY)

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Target: WDHD1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYY-1604

Application*: WB, P

Mouse Anti-WDHD1 Recombinant Antibody (CBYY-1601) (CBMAB-1672-YY)

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Target: WDHD1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYY-1601

Application*: WB

Mouse Anti-WDHD1 Recombinant Antibody (CBYY-1591) (CBMAB-1661-YY)

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Target: WDHD1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse

Clone: CBYY-1591

Application*: WB, IH

Mouse Anti-WDHD1 Recombinant Antibody (CBYY-1586) (CBMAB-1656-YY)

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Target: WDHD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Frog

Clone: CBYY-1586

Application*: C, IC, IP, WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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