WDHD1

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]

WDHD1

Core replisome component that acts as a replication initiation factor. Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork.

Biological Process DNA repair Source:GO_Central1 Publication
Biological Process DNA-templated DNA replication Source:GO_Central1 Publication
Biological Process mitotic cell cycle Source:GO_Central1 Publication

Nucleus, nucleoplasm