WDHD1

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
Full Name
WDHD1
Function
Core replisome component that acts as a replication initiation factor. Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork.
Biological Process
Biological Process DNA repair Source:GO_Central1 Publication
Biological Process DNA-templated DNA replication Source:GO_Central1 Publication
Biological Process mitotic cell cycle Source:GO_Central1 Publication
Cellular Location
Nucleus, nucleoplasm
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Anti-WDHD1 antibodies

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Mouse Anti-WDHD1 Monoclonal Antibody (1B10) (CBMAB-0299-LY)

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Target: WDHD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1B10
Application*: IP, M, WB, CI
Datasheet SDS

Mouse Anti-WDHD1 Monoclonal Antibody (1A5) (CBMAB-0298-LY)

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Target: WDHD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A5
Application*: IP, M, CI
Datasheet SDS

Mouse Anti-WDHD1 Recombinant Antibody (2F10) (CBMAB-A9913-LY)

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Target: WDHD1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2F10
Application*: WB, E
Datasheet SDS

Mouse Anti-WDHD1 Recombinant Antibody (CBYY-1604) (CBMAB-1675-YY)

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Target: WDHD1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-1604
Application*: WB, P
Datasheet SDS

Mouse Anti-WDHD1 Recombinant Antibody (CBYY-1601) (CBMAB-1672-YY)

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Target: WDHD1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-1601
Application*: WB
Datasheet SDS

Mouse Anti-WDHD1 Recombinant Antibody (CBYY-1591) (CBMAB-1661-YY)

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Target: WDHD1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBYY-1591
Application*: WB, IH
Datasheet SDS

Mouse Anti-WDHD1 Recombinant Antibody (CBYY-1586) (CBMAB-1656-YY)

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Target: WDHD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Frog
Clone: CBYY-1586
Application*: C, IC, IP, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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