ZFAND6

Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of Lys-48-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).
Full Name
ZFAND6
Function
Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cellular response to tumor necrosis factor Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process protein targeting to peroxisome Source:UniProtKB
Biological Process regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
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Anti-ZFAND6 antibodies

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Rabbit Anti-ZFAND6 Recombinant Antibody (CBWJZ-004) (CBMAB-Z0010-WJ)

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Target: ZFAND6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBWJZ-004
Application*: WB, F
Datasheet SDS

Mouse Anti-ZFAND6 Antibody (12BA13) (CBMAB-1835CQ)

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Target: ZFAND6
Host: Mouse
Antibody Isotype: IgG2c
Specificity: Human
Clone: 12BA13
Application*: E, WB
Datasheet SDS

Mouse Anti-ZFAND6 Antibody (12BA12) (CBMAB-1834CQ)

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Target: ZFAND6
Host: Mouse
Antibody Isotype: IgG2c
Specificity: Human
Clone: 12BA12
Application*: E, WB
Datasheet SDS

Mouse Anti-ZFAND6 Antibody (12BA11) (CBMAB-1833CQ)

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Target: ZFAND6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12BA11
Application*: E, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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