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ZFAND6

Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of Lys-48-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).

Full Name

ZFAND6

Function

Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).

Biological Process

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cellular response to tumor necrosis factor Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process protein targeting to peroxisome Source:UniProtKB
Biological Process regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication

Cellular Location

Cytoplasm

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Anti-ZFAND6 antibodies

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Rabbit Anti-ZFAND6 Recombinant Antibody (CBWJZ-004) (CBMAB-Z0010-WJ)

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Target: ZFAND6

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: CBWJZ-004

Application*: WB, F

Mouse Anti-ZFAND6 Antibody (12BA13) (CBMAB-1835CQ)

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Target: ZFAND6

Host: Mouse

Antibody Isotype: IgG2c

Specificity: Human

Clone: 12BA13

Application*: E, WB

Mouse Anti-ZFAND6 Antibody (12BA12) (CBMAB-1834CQ)

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Target: ZFAND6

Host: Mouse

Antibody Isotype: IgG2c

Specificity: Human

Clone: 12BA12

Application*: E, WB

Mouse Anti-ZFAND6 Antibody (12BA11) (CBMAB-1833CQ)

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Target: ZFAND6

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 12BA11

Application*: E, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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