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Rabbit Anti-ZFAND6 Recombinant Antibody (CBWJZ-004) (CBMAB-Z0010-WJ)

This product is a rabbit antibody that recognizes ZFAND6. The antibody CBWJZ-004 can be used for immunoassay techniques such as: WB, FC.
See all ZFAND6 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBWJZ-004
Antibody Isotype
IgG
Application
WB, FC

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
ZFAND6
Introduction
ZFAND6 (Zinc Finger AN1-Type Containing 6) involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. It may involved in modulation of Lys-48-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1.
Entrez Gene ID
Human54469
Mouse65098
Rat293067
UniProt ID
HumanQ6FIF0
MouseQ9DCH6
RatQ6DGF4
Alternative Names
AWP1; ZA20D3; ZFAND5B; zinc finger; A20 domain containing 3; AN1-type zinc finger protein 6; protein associated with PRK1; Associated with PRK1 protein; Zinc finger A20 domain-containing protein 3
Function
Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cellular response to tumor necrosis factor Source:UniProtKB1 Publication
Biological Process negative regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process protein targeting to peroxisome Source:UniProtKB
Biological Process regulation of I-kappaB kinase/NF-kappaB signaling Source:UniProtKB1 Publication
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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