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ZFYVE21

ZFYVE21 (Zinc Finger FYVE-Type Containing 21) is a Protein Coding gene. Diseases associated with ZFYVE21 include Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes. An important paralog of this gene is ZFYVE16.

Full Name

Zinc Finger FYVE-Type Containing 21

Function

Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression.

Cellular Location

Cell junction, focal adhesion
Cytoplasmic vesicle
Endosome
Within cytoplasmic vesicles, partially colocalizes with EEA1, an endosomal marker.

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Anti-ZFYVE21 antibodies

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Mouse Anti-ZFYVE21 Recombinant Antibody (2B12) (CBMAB-Z0249-WJ)

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Target: ZFYVE21

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2B12

Application*: WB

Mouse Anti-ZFYVE21 Recombinant Antibody (4A2) (CBMAB-Z0248-WJ)

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Target: ZFYVE21

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4A2

Application*: WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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