ZFYVE21

ZFYVE21 (Zinc Finger FYVE-Type Containing 21) is a Protein Coding gene. Diseases associated with ZFYVE21 include Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes. An important paralog of this gene is ZFYVE16.

Full Name

Zinc Finger FYVE-Type Containing 21

Function

Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression.

Cellular Location

Cell junction, focal adhesion
Cytoplasmic vesicle
Endosome
Within cytoplasmic vesicles, partially colocalizes with EEA1, an endosomal marker.

Anti-ZFYVE21 antibodies

Mouse Anti-ZFYVE21 Recombinant Antibody (4A2) (CBMAB-Z0248-WJ)

Datasheet

SDS

Target: ZFYVE21

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4A2

Application*: WB

Mouse Anti-ZFYVE21 Recombinant Antibody (2B12) (CBMAB-Z0249-WJ)

Datasheet

SDS

Target: ZFYVE21

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2B12

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)