ZNF639
This gene encodes a member of the Kruppel-like zinc finger family of proteins. Amplification and overexpression of this gene have been observed in esophageal squamous cell carcinoma. The encoded protein has been shown to bind DNA in a sequence-specific manner and may regulate HIV-1 gene expression. Alternative splicing results in multiple transcript variants.
Full Name
ZNF639
Function
Binds DNA and may function as a transcriptional repressor.
Biological Process
Biological Process negative regulation by host of viral transcription Source:UniProtKB1 Publication
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process positive regulation by host of viral transcription Source:UniProtKB1 Publication
Biological Process positive regulation of cell growth Source:UniProtKB1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:NTNU_SB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process viral entry into host cell Source:UniProtKB1 Publication
Biological Process negative regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process positive regulation by host of viral transcription Source:UniProtKB1 Publication
Biological Process positive regulation of cell growth Source:UniProtKB1 Publication
Biological Process positive regulation of transcription by RNA polymerase II Source:NTNU_SB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Biological Process viral entry into host cell Source:UniProtKB1 Publication
Cellular Location
Nucleus
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Anti-ZNF639 antibodies
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Target: ZNF639
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2B2
Application*: CI, IP, M, WB
Target: ZNF639
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1F2
Application*: IP, M
Target: ZNF639
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F10
Application*: IP, M, WB
Target: ZNF639
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1E7
Application*: CI, IP, M
Target: ZNF639
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1D3
Application*: IP, M
Target: ZNF639
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJZ-222
Application*: IP, WB
Target: ZNF639
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJZ-221
Application*: IP
Target: ZNF639
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJZ-032
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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