Mouse Anti-CDC42BPG Recombinant Antibody (2C3) (CBMAB-C4776-LY)

Name: Mouse Anti-CDC42BPG Recombinant Antibody (2C3)
SKU: CBMAB-C4776-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2C3

Application

WB, IP, ELISA

Immunogen

Amino acids 1423-1528 representing partial length MRCKγ of human.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
ELISA	1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% gelatin

Preservative

< 0.1% sodium azide

Concentration

0.1 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

CDC42 binding protein kinase gamma (DMPK-like)

Introduction

CDC42BPG (CDC42 Binding Protein Kinase Gamma) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDC42BPA.

Entrez Gene ID

55561

UniProt ID

Q6DT37

Alternative Names

CDC42 Binding Protein Kinase Gamma; Myotonic Dystrophy Kinase-Related CDC42-Binding Kinase Gamma; CDC42 Binding Protein Kinase Gamma (DMPK-Like); Myotonic Dystrophy Protein Kinase-Like Alpha; Myotonic Dystrophy Protein Kinase-Like Gamma; DMPK-Like Gamma;

Function

May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity).

Biological Process

Actin cytoskeleton reorganization Source: UniProtKB
Actomyosin structure organization Source: GO_Central
Intracellular signal transduction Source: InterPro
Peptidyl-threonine phosphorylation Source: GO_Central
Protein phosphorylation Source: UniProtKB

Cellular Location

Cytoplasm. Concentrates at the leading edge of cells.

Yasukochi, Y., Sakuma, J., Takeuchi, I., Kato, K., Oguri, M., Fujimaki, T., ... & Yamada, Y. (2018). Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population. Molecular genetics and genomics, 293(2), 371-379.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Human Recombinant CDC42BPG, Active protein, GST Tag (CAT#: V2LY-0526-LY3001)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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