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Mouse Anti-DNAJA2 Recombinant Antibody (A2302) (CBMAB-D1256-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat, Dog
Clone
A2302
Antibody Isotype
IgG1, κ
Application
IP, WB

Basic Information

Immunogen
Amino acids 294-412 of mouse DnaJA2.
Host Species
Mouse
Specificity
Human, Mouse, Rat, Dog
Antibody Isotype
IgG1, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Gelatin & PBS
Preservative
Sodium Azide
Concentration
0.2 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
DnaJ (Hsp40) homolog, subfamily A, member 2
Introduction
DNAJA2 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.
Entrez Gene ID
Human10294
Dog478143
Rat84026
UniProt ID
HumanO60884
DogE2R7F3
RatO35824
Alternative Names
DnaJ Heat Shock Protein Family (Hsp40) Member A2; Cell Cycle Progression Restoration Gene 3 Protein; DnaJ (Hsp40) Homolog, Subfamily A, Member 2; Renal Carcinoma Antigen NY-REN-14; HIRIP4; DNJ3; CPR3; DJ3; DnaJ Homolog Subfamily A Member 2;
Function
Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).
Biological Process
Positive regulation of cell population proliferation Source: ProtInc
Protein refolding Source: UniProtKB
Response to heat Source: InterPro
Cellular Location
Membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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