Mouse Anti-DNPEP Recombinant Antibody (10B2753) (CBMAB-D1453-YC)

Name: Mouse Anti-DNPEP Recombinant Antibody (10B2753)
SKU: CBMAB-D1453-YC
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

10B2753

Antibody Isotype

IgG1

Application

ELISA, ICC, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-476

Target

Introduction

DNPEP is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins.

Entrez Gene ID

23549

UniProt ID

Q9ULA0

Alternative Names

Aspartyl Aminopeptidase; EC 3.4.11.21; ASPEP; DAP;

Function

Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism.

Biological Process

Peptide metabolic process Source: ProtInc

Cellular Location

Cytoplasm

More Infomation

References

Yuhara, H., Ohtani, A., Matano, M., Kashiwagi, Y., & Maehashi, K. (2021). Molecular characterization of a novel aspartyl aminopeptidase that contributes to the increase in glutamic acid content in chicken meat during cooking. Food Chemistry: Molecular Sciences, 2, 100015.

Geng, N., Li, Y., Zhang, W., Wang, F., Wang, X., Jin, Z., ... & Li, F. (2020). A PAK5–DNPEP–USP4 axis dictates breast cancer growth and metastasis. International Journal of Cancer, 146(4), 1139-1151.

Geng, N., Zhang, W., Li, Y., & Li, F. (2019). Aspartyl aminopeptidase suppresses proliferation, invasion, and stemness of breast cancer cells via targeting CD44. The Anatomical Record, 302(12), 2178-2185.

Koumangoye, R., & Delpire, E. (2017). DNPEP is not the only peptidase that produces SPAK fragments in kidney. Physiological Reports, 5(21), e13479.

Park, S. Y., Scranton, M. A., Stajich, J. E., Yee, A., & Walling, L. L. (2017). Chlorophyte aspartyl aminopeptidases: Ancient origins, expanded families, new locations, and secondary functions. PloS one, 12(10), e0185492.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-DNPEP Recombinant Antibody (D1453) (CAT#: V2LY-0425-LY747)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote
Second antibody and isotype control

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