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Mouse Anti-GJD2 Recombinant Antibody (CBLG1-1219) (CBMAB-G3597-LY)


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Summary

Host Animal
Mouse
Specificity
Mouse
Clone
CBLG1-1219
Antibody Isotype
IgG1
Application
IHC-F, IP, WB

Basic Information

Immunogen
Synthetic peptide derived from the C-terminal region of the rat and mouse Connexin36 proteins. This sequence differs from the human Connexin36 sequence by one amino acid
Specificity
Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.25 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
gap junction protein, delta 2, 36kDa
Introduction
This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. [provided by RefSeq, Oct 2012]
Entrez Gene ID
14617
UniProt ID
O54851
Alternative Names
Gja9; connexin36; cx36
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Biological Process
Cell-cell signaling Source: GO_Central
Cellular Location
Cell membrane; Gap junction
Topology
Cytoplasmic: 1-19
Helical: 20-42
Extracellular: 43-75
Helical: 76-98
Cytoplasmic: 99-197
Helical: 198-220
Extracellular: 221-252
Helical: 253-275
Cytoplasmic: 276-321
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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