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Mouse Anti-hdc Antibody (HDC U33) (CBMAB-1318CQ)


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Summary

Host Animal
Mouse
Specificity
Common fruit fly
Clone
HDC U33
Antibody Isotype
IgG1
Application
IF, IHC, IP, WB

Basic Information

Immunogen
Recombinant headcase protein (aa 44-462)
Specificity
Common fruit fly
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 44-462

Target

Full Name
Hdc
Introduction
Required for imaginal cell differentiation, may be involved in hormonal responsiveness during metamorphosis. Involved in an inhibitory signaling mechanism to determine the number of cells that will form unicellular sprouts in the trachea. Regulated by transcription factor esg. The longer hdc protein is completely functional and the shorter protein carries some function.
Entrez Gene ID
43604
UniProt ID
Q9N2M8
Alternative Names
hdc; Headcase
Function
Required for imaginal cell differentiation, may be involved in hormonal responsiveness during metamorphosis. Involved in an inhibitory signaling mechanism to determine the number of cells that will form unicellular sprouts in the trachea. Regulated by transcription factor esg. The longer hdc protein is completely functional and the shorter protein carries some function.
Biological Process
Instar larval or pupal development Source: UniProtKB
Negative regulation of neurogenesis Source: FlyBase
Regulation of neuron remodeling Source: FlyBase
RNA interference Source: FlyBase
Salivary gland cell autophagic cell death Source: FlyBase
Terminal branching, open tracheal system Source: UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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