Rabbit Anti-PHYKPL Recombinant Antibody (EG104) (CBMAB-EN113-LY)

Name: Rabbit Anti-PHYKPL Recombinant Antibody (EG104)
SKU: CBMAB-EN113-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

EG104

Application

WB: 1:500~1:1000 ELISA: 1:10000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human AGXT2L2.

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

5-Phosphohydroxy-L-Lysine Phospho-Lyase

Introduction

This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Entrez Gene ID

Human	85007
Mouse	72947
Rat	100169747

UniProt ID

Human	Q8IUZ5
Mouse	Q8R1K4
Rat	B0BNC4

Alternative Names

5-Phosphohydroxy-L-Lysine Phospho-Lyase; Alanine--Glyoxylate Aminotransferase 2-Like 2; 5-Phosphonooxy-L-Lysine Phospho-Lyase; AGXT2L2; Alanine-Glyoxylate Aminotransferase 2-Like 2; EC 4.2.3.134;

Function

Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde.

Cellular Location

Mitochondrion

Involvement in disease

Phosphohydroxylysinuria (PHLU):
A condition characterized by elevated phosphohydroxylysine in the urine. There is no clinical phenotype associated with this finding other than the urinary metabolites.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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