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Rabbit Anti-PHYKPL Recombinant Antibody (EG104) (CBMAB-EN113-LY)

The product is antibody recognizes PHYKPL . The antibody EG104 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:10000.
See all PHYKPL antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG104
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:10000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human AGXT2L2.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
5-Phosphohydroxy-L-Lysine Phospho-Lyase
Introduction
This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Entrez Gene ID
Human85007
Mouse72947
Rat100169747
UniProt ID
HumanQ8IUZ5
MouseQ8R1K4
RatB0BNC4
Alternative Names
5-Phosphohydroxy-L-Lysine Phospho-Lyase; Alanine--Glyoxylate Aminotransferase 2-Like 2; 5-Phosphonooxy-L-Lysine Phospho-Lyase; AGXT2L2; Alanine-Glyoxylate Aminotransferase 2-Like 2; EC 4.2.3.134;
Function
Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde.
Cellular Location
Mitochondrion
Involvement in disease
Phosphohydroxylysinuria (PHLU):
A condition characterized by elevated phosphohydroxylysine in the urine. There is no clinical phenotype associated with this finding other than the urinary metabolites.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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