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Mouse Anti-PTP4A1/PTP4A3 Recombinant Antibody (CBYC-P773) (CBMAB-P3403-YC)

Provided herein is a Mouse monoclonal antibody against Human Protein tyrosine phosphatase type IVA. The antibody can be used for immunoassay techniques, such as IHC.
See all PTP4A1/PTP4A3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-P773
Antibody Isotype
IgG2b
Application
IHC

Basic Information

Immunogen
E. coli-derived Recombinant human PRL-3, Ala2-Met173
Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized from PBS with trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Protein tyrosine phosphatase type IVA, member 1
Introduction
This gene encode members of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The protein are cell signaling molecules that play regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis.
Entrez Gene ID
7803
UniProt ID
Q93096
Alternative Names
HH72; PTPCAAX1; PTP(CAAX1); PRL3; PRL1; PRL-1; PRL-R; PRL-3
Function
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.
Biological Process
Cell cycleIEA:UniProtKB-KW
Positive regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Protein dephosphorylationIEA:InterPro
Cellular Location
Cell membrane
Early endosome
Endoplasmic reticulum
Cytoplasm
Cytoplasm, cytoskeleton, spindle
Nucleus
And mitotic spindle.
PTM
Farnesylated. Farnesylation is required for membrane targeting. Unfarnesylated forms are shifted into the nucleus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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