Mouse Anti-RAB39B Recombinant Antibody (1E11) (CBMAB-R0840-CN)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:27103069).
May regulate the homeostasis of SNCA/alpha-synuclein. Together with PICK1 proposed to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR compostion at the post-synapses and thus synaptic transmission (By similarity).
Biological Process protein transportIEA:UniProtKB-KW
Biological Process Rab protein signal transductionIEA:InterPro
Biological Process regulation of autophagyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process synapse organizationISS:UniProtKB
Biological Process vesicle-mediated transportISS:UniProtKB
Cytoplasmic vesicle membrane
Golgi apparatus
Partial colocalization with markers that cycle from the cell surface to the trans-Golgi network.
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked forms, while syndromic forms present with associated physical, neurological and/or psychiatric manifestations. XLID72 patients can manifest autism spectrum disorder, seizures and macrocephaly as additional features.
Waisman syndrome (WSMN):
A neurologic disorder characterized by delayed psychomotor development, intellectual disability, and early-onset Parkinson disease.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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