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Mouse Anti-REV3L Recombinant Antibody (CBCNR-420) (CBMAB-R2294-CN)

This product is a Mouse antibody that recognizes REV3L. The antibody CBCNR-420 can be used for immunoassay techniques such as: WB.
See all REV3L antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-420
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
REV3 Like, DNA Directed Polymerase Zeta Catalytic Subunit
Introduction
The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome. [provided by RefSeq, Jan 2017]
Entrez Gene ID
5980
UniProt ID
O60673
Alternative Names
REV3 Like, DNA Directed Polymerase Zeta Catalytic Subunit; REV3-Like, Polymerase (DNA Directed), Zeta, Catalytic Subunit; EC 2.7.7.7; POLZ; REV3; REV3 (Yeast Homolog)-Like, Catalytic Subunit Of DNA Polymerase Zeta; REV3-Like, Catalytic Subunit Of DNA Polymerase Zeta (Yeast); Rev-3, Yeast, Homolog-Like (Polymerase, DNA, Zeta);
Function
Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function.
Biological Process
Biological Process DNA-templated DNA replicationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process double-strand break repair via homologous recombinationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process error-prone translesion synthesisManual Assertion Based On ExperimentIDA:ComplexPortal
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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