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Mouse Anti-RNF182 Recombinant Antibody (CBCNR-595) (CBMAB-R2973-CN)

This product is a Mouse antibody that recognizes RNF182. The antibody CBCNR-595 can be used for immunoassay techniques such as: ELISA, WB.
See all RNF182 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-595
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
RNF182 (NP_689950, aa. 1-99) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
1× PBS, pH 7.2

Target

Full Name
ring finger protein 182
Introduction
RNF182 (Ring Finger Protein 182) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin-protein transferase activity.
Entrez Gene ID
221687
UniProt ID
Q8N6D2
Alternative Names
Ring Finger Protein 182; RING Finger Protein 182; RING-Type E3 Ubiquitin Transferase RNF182; EC 2.3.2.27;
Function
E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843).
Also plays a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514).
Biological Process
Protein ubiquitination
Cellular Location
Membrane
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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