Mouse Anti-RNF182 Recombinant Antibody (CBCNR-595) (CBMAB-R2973-CN)

Name: Mouse Anti-RNF182 Recombinant Antibody (CBCNR-595)
SKU: CBMAB-R2973-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBCNR-595

Application

ELISA, WB

Immunogen

RNF182 (NP_689950, aa. 1-99) partial recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

1× PBS, pH 7.2

More Infomation

Target

Full Name

ring finger protein 182

Introduction

RNF182 (Ring Finger Protein 182) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin-protein transferase activity.

Entrez Gene ID

221687

UniProt ID

Q8N6D2

Alternative Names

Ring Finger Protein 182; RING Finger Protein 182; RING-Type E3 Ubiquitin Transferase RNF182; EC 2.3.2.27;

Function

E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843).
Also plays a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514).

Biological Process

Protein ubiquitination

Cellular Location

Membrane
Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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