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Mouse Anti-SMCP Recombinant Antibody (CBXS-0559) (CBMAB-S3502-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-0559
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
SMCP (AAH14593, 1 a.a.-116 a.a) Full length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Ascites fluid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
sperm mitochondria-associated cysteine-rich protein
Introduction
Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath.
Entrez Gene ID
4184
UniProt ID
P49901
Alternative Names
Sperm Mitochondria Associated Cysteine Rich Protein; MCSP; MCS; Sperm Mitochondrial-Associated Cysteine-Rich Protein; Sperm Mitochondria-Associated Cysteine-Rich Protein; Mitochondrial Capsule Selenoprotein; Testicular Tissue Protein Li 119; Testicular Tissue Protein Li 161; HSMCSGEN1;
Function
Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida (By similarity).
Biological Process
Biological Process flagellated sperm motilityISS:UniProtKB
Biological Process penetration of zona pellucidaISS:UniProtKB
Cellular Location
Cytoplasm
Mitochondrion membrane
Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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