Sign in or Register   Sign in or Register
  |  

Mouse Anti-SSR4 Recombinant Antibody (CBXS-4299) (CBMAB-S0236-CQ)

This product is a mouse antibody that recognizes SSR4. The antibody CBXS-4299 can be used for immunoassay techniques such as: WB, ELISA.
See all SSR4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4299
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
Recombinant human SSR4 (24-144aa) purified from E. coli
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
signal sequence receptor, delta (translocon-associated protein delta)
Introduction
This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.
Entrez Gene ID
6748
UniProt ID
P51571
Alternative Names
Signal Sequence Receptor Subunit 4; Signal Sequence Receptor, Delta; TRAP-Delta; SSR-Delta; TRAPD; Translocon-Associated Protein Subunit Delta; Signal Sequence Receptor Subunit Delta; Translocon-Associated Protein Delta; CDG1Y;
Function
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Cellular Location
Endoplasmic reticulum membrane
Involvement in disease
Congenital disorder of glycosylation 1Y (CDG1Y):
A form of congenital disorder of glycosylation, a multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
Topology
Lumenal: 24-144
Helical: 145-165
Cytoplasmic: 166-173
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-SSR4 Recombinant Antibody (CBXS-4299)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare