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Mouse Anti-STAC Recombinant Antibody (CBXS-4444) (CBMAB-S1686-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4444
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
STAC (AAH20221, 209 a.a.-318 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
STAC
Entrez Gene ID
6769
UniProt ID
Q99469
Alternative Names
STAC1
Function
Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C.
Biological Process
Biological Process cellular response to heatIEA:Ensembl
Biological Process positive regulation of cation channel activityISS:UniProtKB
Biological Process positive regulation of protein localization to plasma membraneISS:UniProtKB
Biological Process positive regulation of voltage-gated calcium channel activityISS:UniProtKB
Biological Process signal transduction1 PublicationNAS:UniProtKB
Biological Process skeletal muscle contractionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm, cytosol
Cell membrane
Cell membrane, sarcolemma
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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