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Mouse Anti-STING1 Recombinant Antibody (CBXS-1907) (CBMAB-S0136-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-1907
Antibody Isotype
IgG2b
Application
ICFC

Basic Information

Immunogen
Recombinant human STING/TMEM173, Ala215-Ser379, Accession # Q86WV6
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
A saline solution, BSA
Preservative
Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
STING1
Introduction
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Entrez Gene ID
340061
UniProt ID
Q86WV6
Alternative Names
Transmembrane Protein 173; Endoplasmic Reticulum Interferon Stimulator; HSTING; STING; HMITA; ERIS; MITA; N-Terminal Methionine-Proline-Tyrosine-Serine Plasma Membrane Tetraspanner; Mitochondrial Mediator Of IRF3 Activation;
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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