Mouse Anti-ZNFX1 Recombinant Antibody (6F9) (CBMAB-Z0689-WJ)

Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Acts as a double-stranded RNA (dsRNA) sensor that recognizes viral RNA and then interacts with MAVS to initiate the type I interferon response (By similarity).
Also required for immunity against some bacteria, such as mycobacteria (PubMed:33876776).
Biological Process defense response to bacterium Source:UniProtKB1 Publication
Biological Process defense response to virus Source:UniProtKB1 Publication
Biological Process innate immune response Source:UniProtKB-KW
Biological Process negative regulation of viral genome replication Source:UniProtKB
Biological Process RNA-mediated heterochromatin formation Source:GO_Central1 Publication
Cytoplasm, Stress granule
An autosomal recessive disorder characterized by immunodeficiency, recurrent infections, and hyperinflammation with systemic involvement. Most patients eventually develop hepatic or renal failure, may have compromised neurologic function, lymphadenopathy or hepatosplenomegaly. Early death often occurs due to multiorgan failure.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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