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MALT1 Matched Antibody Pair (711) (APMAB-711LY)

This antibody pair set can be used for detecting and quantifying protein level of human MALT1.
See all MALT1 antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-MALT1 polyclonal antibody, 100 ug
Detection Antibody
Anti-MALT1 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Alternative Names
MALT1 Paracaspase; Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1; MALT Lymphoma-Associated Translocation; MALT1 Protease; Paracaspase; MLT; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1; Caspase-Like Protein;
Entrez Gene ID
10892
UniProt ID
Q9UDY8

Seshadri, M. R., & Melnick, A. M. (2022). Targeting MALT1 for the treatment of diffuse large B-cell lymphoma. Leukemia & Lymphoma, 63(4), 789-798.

Gomez Solsona, B., Schmitt, A., Schulze-Osthoff, K., & Hailfinger, S. (2022). The Paracaspase MALT1 in cancer. Biomedicines, 10(2), 344.

Sefer, A. P., Abolhassani, H., Ober, F., Kayaoglu, B., Bilgic Eltan, S., Kara, A., ... & Baris, S. (2022). Expanding the clinical and immunological phenotypes and natural history of MALT1 deficiency. Journal of clinical immunology, 42(3), 634-652.

Hamp, I., O’Neill, T. J., Plettenburg, O., & Krappmann, D. (2021). A patent review of MALT1 inhibitors (2013-present). Expert Opinion on Therapeutic Patents, 31(12), 1079-1096.

Liang, X., Cao, Y., Li, C., Yu, H., Yang, C., & Liu, H. (2021). MALT1 as a promising target to treat lymphoma and other diseases related to MALT1 anomalies. Medicinal Research Reviews, 41(4), 2388-2422.

Lu, H. Y., & Turvey, S. E. (2021). Human MALT1 deficiency and predisposition to infections. Current Opinion in Immunology, 72, 1-12.

O’Neill, T. J., Seeholzer, T., Gewies, A., Gehring, T., Giesert, F., Hamp, I., ... & Krappmann, D. (2021). TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease. Science immunology, 6(65), eabh2095.

Ruland, J., & Hartjes, L. (2019). CARD–BCL-10–MALT1 signalling in protective and pathological immunity. Nature Reviews Immunology, 19(2), 118-134.

Quancard, J., Klein, T., Fung, S. Y., Renatus, M., Hughes, N., Israël, L., ... & Overall, C. M. (2019). An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nature chemical biology, 15(3), 304-313.

Gehring, T., Erdmann, T., Rahm, M., Graß, C., Flatley, A., O’Neill, T. J., ... & Krappmann, D. (2019). MALT1 phosphorylation controls activation of T lymphocytes and survival of ABC-DLBCL tumor cells. Cell Reports, 29(4), 873-888.

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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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