Mouse Recombinant IGSF8 protein, His Tag (V2LY-0526-LY8452)

Name: Mouse Recombinant IGSF8 protein, His Tag
SKU: V2LY-0526-LY8452
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Mouse

Tag

His Tag

Protein Construction

This product is Mouse Recombinant IGSF8 protein, His Tag consist of Amino Acid: 1-577 and predicts a molecular mass of 60.2 kDa.

Molecule Mass

60.2 kDa

Sequence

Amino Acid: 1-577

Species

Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>95% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

immunoglobulin superfamily, member 8

Function

May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

Biological Process

Cell motility Source: UniProtKB
Nervous system development Source: UniProtKB
Single fertilization Source: UniProtKB
Skeletal muscle tissue development Source: UniProtKB

Cellular Location

Cell membrane

Topology

Extracellular: 28-579
Helical: 580-600
Cytoplasmic: 601-613

Apóstolo, N., Smukowski, S. N., Vanderlinden, J., Condomitti, G., Rybakin, V., Ten Bos, J., ... & de Wit, J. (2020). Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer. Nature communications, 11(1), 5171.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus, Rhesus Recombinant IGSF8 protein, His Tag (CAT#: V2LY-0526-LY1717)

Human Recombinant IGSF8 protein, His Tag (CAT#: V2LY-0526-LY4696)

Mouse Recombinant IGSF8 protein, hFc Tag (CAT#: V2LY-0526-LY8451)

Related Products

Cynomolgus, Rhesus Recombinant IGSF8 protein, His Tag (CAT#: V2LY-0526-LY1717)

Mouse Recombinant IGSF8 protein, hFc Tag (CAT#: V2LY-0526-LY8451)

Mouse Anti-IGSF8 Recombinant Antibody (CBWJC-3802) (CAT#: CBMAB-C5071WJ)

Mouse Anti-IGSF8 Recombinant Antibody (CBXC-0656) (CAT#: CBMAB-C3219-CQ)

Human Recombinant IGSF8 protein, His Tag (CAT#: V2LY-0526-LY4696)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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