ADAMTSL1

This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins.
Full Name
Adamts Like 1
Biological Process
Extracellular matrix organization
Cellular Location
Extracellular matrix
PTM
C-, N- and O-glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTSL1. Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion.
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Anti-ADAMTSL1 antibodies

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Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-179858) (CBMAB-A1228-YC)

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Target: ADAMTSL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-179858
Application*: E, IP, WB
Datasheet SDS

Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-606566) (CBMAB-X0217-FY)

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Target: ADAMTSL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-606566
Application*: IA, WB
Datasheet SDS

Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-179859) (CBMAB-A1229-YC)

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Target: ADAMTSL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-179859
Application*: IP, WB
Datasheet SDS

Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-179857) (CBMAB-A1227-YC)

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Target: ADAMTSL1
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: V2-179857
Application*: WB
Datasheet SDS

Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-179853) (CBMAB-A1223-YC)

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Target: ADAMTSL1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: V2-179853
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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