Human Recombinant ADAMTSL1 protein, His Tag (V2LY-0526-LY1938)

Name: Human Recombinant ADAMTSL1 protein, His Tag
SKU: V2LY-0526-LY1938
Rating: 5 (1 reviews)

See all ADAMTSL1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant ADAMTSL1 protein, His Tag consist of Amino Acid: 1-439 and predicts a molecular mass of 47.1 kDa.

Molecule Mass

47.1 kDa

Sequence

Amino Acid: 1-439

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>95% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Adamts Like 1

Biological Process

Extracellular matrix organization

Cellular Location

Extracellular matrix

PTM

C-, N- and O-glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTSL1. Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion.

Kantaputra, P. N., Pruksametanan, A., Phondee, N., Hutsadaloi, A., Intachai, W., Kawasaki, K., ... & Tripuwabhrut, P. (2019). ADAMTSL1 and mandibular prognathism. Clinical genetics, 95(4), 507-515.

Vorkapic, E., Folkesson, M., Magnell, K., Bohlooly-Y, M., Länne, T., & Wågsäter, D. (2017). ADAMTS-1 in abdominal aortic aneurysm. PLoS One, 12(6), e0178729.

Hendee, K., Wang, L. W., Reis, L. M., Rice, G. M., Apte, S. S., & Semina, E. V. (2017). Identification and functional analysis of an ADAMTSL1 variant associated with a complex phenotype including congenital glaucoma, craniofacial, and other systemic features in a three‐generation human pedigree. Human mutation, 38(11), 1485-1490.

Kadalayil, L., Khan, S., Nevanlinna, H., Fasching, P. A., Couch, F. J., Hopper, J. L., ... & Tapper, W. (2017). Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women. Nature communications, 8(1), 1-12.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant ADAMTSL1 protein, His Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-179858) (CAT#: CBMAB-A1228-YC)

Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-179859) (CAT#: CBMAB-A1229-YC)

Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-179853) (CAT#: CBMAB-A1223-YC)

Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-179857) (CAT#: CBMAB-A1227-YC)

Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-606566) (CAT#: CBMAB-X0217-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry