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Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-179857) (CBMAB-A1227-YC)

Provided herein is a Mouse monoclonal antibody against Human ADAMTS Like 1. The antibody can be used for immunoassay techniques, such as WB.
See all ADAMTSL1 antibodies
Published Data
Mouse Anti-ADAMTSL1 Recombinant Antibody (30D445.1) (CBMAB-A1227-YC) in WB
Western blot analysis of ADAMTS-1 and GAPDH expression in normoxic conditions. ...View More
Turkoglu, S. A., & Kockar, F. (2016). SP1 and USF differentially regulate ADAMTS1 gene expression under normoxic and hypoxic conditions in hepatoma cells. Gene, 575(1), 48-57.

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-179857
Antibody Isotype
IgM
Application
WB

Basic Information

Immunogen
Synthetic peptide (Human)
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:5,000
IP1-2 µl per 100-500 µg of total protein (1 ml of cell lysate).

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Ascites
Preservative
< 0.1% sodium azide
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Adamts Like 1
Introduction
ADAMTSL1 is a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains oth
Entrez Gene ID
92949
UniProt ID
Q8N6G6
Alternative Names
ADAMTS Like 1; Punctin-1; ADAMTSL-1; ADAMTSR1; Punctin; C9orf94; Chromosome 9 Open Reading Frame 94; ADAM-TS Related Protein 1; ADAMTS-Like Protein 1;
Biological Process
Extracellular matrix organization
Cellular Location
Extracellular matrix
PTM
C-, N- and O-glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTSL1. Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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