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Mouse Anti-ADAMTSL1 Recombinant Antibody (V2-606566) (CBMAB-X0217-FY)

This product is mouse antibody that recognizes ADAMTSL1. The antibody 1B2-8-2 can be used for immunoassay techniques such as: Immunoassay, WB.
See all ADAMTSL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-606566
Antibody Isotype
IgG2b
Application
IA, WB

Basic Information

Immunogen
Monoclonal antibody 1B2-8-2 reacts with Punctin-1.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% BSA
Preservative
0.02% sodium azide
Concentration
0.1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Adamts Like 1
Introduction
This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins.
Entrez Gene ID
92949
UniProt ID
Q8N6G6
Alternative Names
ADAMTS Like 1; Punctin-1; ADAMTSL-1; ADAMTSR1; Punctin; C9orf94; Chromosome 9 Open Reading Frame 94; ADAM-TS Related Protein 1; ADAMTS-Like Protein 1
Biological Process
Extracellular matrix organization
Cellular Location
Extracellular matrix
PTM
C-, N- and O-glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTSL1. Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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