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AK9

The protein encoded by this gene catalyzes the interconversion of nucleosides, possessing both nucleoside monophosphate and diphosphate kinase activities. The encoded protein uses these interconversions to maintain nucleoside homeostasis. [provided by RefSeq, Jul 2016]
Full Name
Adenylate Kinase 9
Function
Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP> UDP> ADP> GDP> TDP.
Biological Process
AMP phosphorylation Source: UniProtKB
ATP generation from ADP Source: UniProtKB
CDP phosphorylation Source: UniProtKB
CMP phosphorylation Source: UniProtKB
dADP phosphorylation Source: UniProtKB
dAMP phosphorylation Source: UniProtKB
dCDP phosphorylation Source: UniProtKB
dCMP phosphorylation Source: UniProtKB
dGDP phosphorylation Source: UniProtKB
GDP phosphorylation Source: UniProtKB
Nucleobase-containing small molecule interconversion Source: Reactome
TDP phosphorylation Source: UniProtKB
UDP phosphorylation Source: UniProtKB
Cellular Location
Nucleus; Cytoplasm

Anti-AK9 antibodies

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Target: AK9
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-180432
Application*: E, IC, IF, IH
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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