AKTIP

The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered p
Full Name
AKT Interacting Protein
Function
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
Biological Process
Apoptotic process Source: UniProtKB-KW
Early endosome to late endosome transport Source: UniProtKB
Endosome organization Source: UniProtKB
Endosome to lysosome transport Source: UniProtKB
Lysosome organization Source: UniProtKB
Positive regulation of protein binding Source: MGI
Positive regulation of protein phosphorylation Source: MGI
Protein polyubiquitination Source: GO_Central
Protein transport
Cellular Location
Cell membrane; Cytoplasm
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Anti-AKTIP antibodies

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Mouse Anti-AKTIP Recombinant Antibody (V2-613690) (CBMAB-A3218-LY)

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Target: AKTIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-613690
Application*: WB, E
Datasheet SDS

Mouse Anti-AKTIP Recombinant Antibody (V2-160821) (CBMAB-F0749-CQ)

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Target: AKTIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: V2-160821
Application*: WB, P, E
Datasheet SDS

Mouse Anti-AKTIP Recombinant Antibody (V2-12570) (CBMAB-1060-CN)

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Target: AKTIP
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: V2-12570
Application*: WB, E
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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