ARHGAP42

This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
Full Name
Rho GTPase Activating Protein 42
Function
May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle.
Biological Process
Activation of GTPase activity Source: UniProtKB
Negative regulation of Rho protein signal transduction Source: Ensembl
Negative regulation of systemic arterial blood pressure Source: Ensembl
Negative regulation of vascular associated smooth muscle contraction Source: Ensembl
Signal transduction Source: InterPro
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Anti-ARHGAP42 antibodies

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Rabbit Anti-ARHGAP42 (Phosphorylated Y376) Recombinant Antibody (D45E9) (PTM-CBMAB-0044YC)

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Target: ARHGAP42
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Monkey
Clone: D45E9
Application*: WB, IP
Datasheet SDS

Mouse Anti-ARHGAP42 Recombinant Antibody (CBT3338) (V2LY-0625-LY625)

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Target: ARHGAP42
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3338
Application*: WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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